Dr Karim Kohansal Vajargah

Dr Karim Kohansal Vajargah

MD

Director of Medical Sciences

Karim is a clinician scientist with a background in cardiovascular medicine and a focus on statistical genetics. He earned his Doctor of Medicine from Shahid Beheshti University of Medical Sciences in Tehran.

He has over three years of clinical experience as a general practitioner and has contributed to more than a dozen peer-reviewed publications in leading cardiovascular journals. His research focuses on the links between heart failure, kidney function and metabolic health, using human genetics, multi-omics and Mendelian randomisation to uncover causal mechanisms and therapeutic targets in vascular ageing and heart failure.

As Director of Medical Sciences at Sequoia Genetics, Karim ensures that the company's work is grounded in disease biology, clinical practice and the realities of drug development. He leads the clinical interpretation of sophisticated human genetic analyses, translating them into actionable insights on target validation, indication selection, patient populations, biomarkers, efficacy and safety for clients across the pharmaceutical and biotechnology sectors. He leads high-priority projects and client engagements, and mentors and develops members of Sequoia's scientific team.