Sequoia Genetics is a UK-based private limited company founded in 2024. It uses human genetic data to generate translational insights for drug discovery and development, serving pharma, biotech, investors, and academia.

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Location Translation and Innovation Hub, 84 Wood Lane, White City, London, W12 0BZ
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Location Translation and Innovation Hub, 84 Wood Lane, White City, London, W12 0BZ
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Human Genetic Evidence to Inform Clinical Development of IL-6 Signaling Inhibition for Abdominal Aortic Aneurysm

Background

Abdominal aortic aneurysm (AAA) represents a significant cause of mortality, yet no medical therapies have proven efficacious. The aim of the current study was to leverage human genetic evidence to inform clinical development of IL-6 (interleukin-6) signaling inhibition for the treatment of AAA.

Findings

Abdominal aortic aneurysm (AAA) represents a significant cause of mortality, yet no medical therapies have proven efficacious. The aim of the current study was to leverage human genetic evidence to inform clinical development of IL-6 (interleukin-6) signaling inhibition for the treatment of AAA.

Conclusions

Abdominal aortic aneurysm (AAA) represents a significant cause of mortality, yet no medical therapies have proven efficacious. The aim of the current study was to leverage human genetic evidence to inform clinical development of IL-6 (interleukin-6) signaling inhibition for the treatment of AAA.

 

Published